Carlisle is a tiny town located in the state of Indiana. With a population of 616 people and two associated neighborhoods, Carlisle is the 379th largest community in Indiana. Carlisle has a large stock of pre-World War II architecture, making it one of the older and more historic towns in the country.

Being a small town, Carlisle does not have a public transit system used by locals to get to and from work.

The citizens of Carlisle have a very low rate of college education: just 9.75% of people over 25 have a bachelor's degree or advanced degree, compared to a national average of 21.84% for all cities.

The per capita income in Carlisle in 2022 was $24,232, which is low income relative to Indiana and the nation. This equates to an annual income of $96,928 for a family of four. However, Carlisle contains both very wealthy and poor people as well.

The people who call Carlisle home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Carlisle residents report their race to be White, followed by Black or African-American. Important ancestries of people in Carlisle include English, German, Irish, Scots-Irish, and Swedish.

The most common language spoken in Carlisle is English. Other important languages spoken here include Polish and Greek.